Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

General description

A potent and selective inhibitor of poly(ADP-ribose) polymerase (PARP; IC₅₀ = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.

A very potent and selective poly(ADP-ribose)polymerase (PARP) inhibitor (IC₅₀ = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Eliasson, M.J., et al. 1997. Nat. Med. 3, 1089.Takahashi, K., et al. 1997. J. Cereb. Blood Flow Metabl. 17, 1137.Suto, M.J., et al. 1991. Anticancer Drug Des. 6, 107.

Packaging

1 mg in Plastic ampoule

Warning

Toxicity: Harmful (C)